E. von Behring Chair in Neuromuscular and Neurodegenerative Disorders
Faculteit
Geneeskunde
Schenker
Bekijk de diavoorstelling van de inhuldiging (6 januari 2010)
Datum ondertekening
24 october 2006
6 january 2010
Duur
3 years (2007 - 2009)
3 years (2010 – 2012)Doelstelling
The prevalence of neurological disorders will dramatically grow during the coming decennia and is likely to represent a major burden to health care systems of Western societies. The unravelling of the pathogenesis of these disorders and the development of therapies for them is a major task for basic and clinical neuroscience research, to which CSL Behring intends to contribute through the installation of the E. von Behring Chair in Neuromuscular and Neurodegenerative Disorders.
Axonal degeneration is a common theme of degenerative and inflammatory disorders affecting the peripheral and central nervous system. Examples are Alzheimer disease, Parkinson’s, amyotrophic lateral sclerosis and Charcot-Marie-Tooth’s disease, but also multiple sclerosis and chronic inflammatory demyelinating polyneuropathy. While immunological mechanisms have always been considered characteristic for inflammatory diseases, recent evidence shows that an immune-mediated component is also involved in the pathogenesis of neurodegenerative disease and that it may even represent a therapeutic target.
