Events Optec Agenda Detail
"MIXED-INTEGER DYNAMIC OPTIMIZATION IN
SYSTEMS BIOLOGY"
Julio R. Banga, IIM-CSIC, Vigo,
Spain
Abstract
Mathematical optimization aims to make a
system or design as effective or
functional as possible, computing
the quality of the different
alternatives using a mathematical
model. Most models in systems biology
have a dynamic nature,
usually described by sets of differential
equations. Dynamic
optimization addresses this class of systems, seeking
the
computation of the optimal time-varying conditions (control
variables)
to minimize or maximize a certain performance index.
Dynamic optimization
can solve many important problems in systems
biology, including optimal
control for obtaining a desired
biological performance, the analysis of
network designs and
computer aided design of biological units.
In this talk I will
describe our research in continuous and mixed-integer
dynamic
optimization (MIDO) problems in the framework of
computational
systems biology. I will also present results
for
several challenging optimization problems related with
bioreactor
optimization, optimal drug infusion
to a patient and
the minimization of intracellular oscillations.
| http://www.kuleuven.be/optec/event/1187 | |
| Seminar | |
| iCal |
Two OPTEC professors have been awarded three "Gouden Krijtjes", the yearly teaching awards given by the organization of engineering students (vtk). Prof. Lombaert was awarded the prize for the best course in civil engineering, and Prof. Diehl the prizes for the best professor and the best course in mathematical engineering (where he teaches numerical optimization). They received these awards at the yearly "proffentap" where experienced students taught them how to draft beer professionally.
