Stevin Lecture today in Aud. De Molen (4pm)
Dear OPTEC Members and Friends,
please note that today's Stevin lecture is in the
*** Auditorium De Molen *** 50 m left of the castle at the Dijle,
in the building near the watermill. It is at 4pm,
see the abstract below.
Also note the other interesting events on
http://www.kuleuven.be/optec/event
(Biegler-DYSCO / Robotics Day)
Best regards,
Moritz
**********
Mon 28 Nov 2011 16:00-17:30, Auditorium De Molen - Arenberg Castle
21st Simon Stevin Lecture on Optimization in Engineering, and
3rd Chemical Engineering Department Lecture (International Year of Chemistry)
"Online Optimization of Biochemical Processes"
Michel Perrier
Department of Chemical Engineering at Polytechnique Montréal
Abstract
Optimization methods have been widely used in biology related fields with great success for example in systems biology, metabolic engineering, biochemical engineering amongst others. Most of the work has been focused on developing mathematical models trying to describe the steady-state and dynamical behaviour obtained from the observation of living organisms at the scale of single cell up to biochemical reactors. Optimization is then performed typically offline to obtain a better understanding of the organism under study from a design or operational standpoint. Comparatively, fewer studies have been performed with the objective of optimizing a specified performance index on-line.
There are many problems specifically associated with online optimization compared to off-line. Model mismatch, model uncertainty, unmeasured disturbances have to be taken into account to make sure to optimize the actual system and not the model. The number of degrees of freedom is also much lower. Methods on how to address these problems will be given by studying several applications to biochemical systems with a focus on bioreactors. Perspectives for future research will be outlined.
Biographical Information
Prof. Michel Perrier is presently Head of the Department of Chemical Engineering at Polytechnique Montréal since Dec. 2009. He obtained his Ph.D. from McGill University. Before joining Polytechnique as a professor in 1993, he worked in industry as a control engineer for a period of seven years at Shell Canada, the Pulp and Paper Research Institute of Canada and the Biotechnology Research Institute in Montréal. He has been a visiting professor at the Centre for Integrated Dynamics and Control in the department of Electrical Engineering at the University of Newcastle in Australia in 2001, at the Centre for Systems Engineering and Applied Mechanics at the Université Catholique de Louvain in Belgium in 2002, and at University Polytechnic of Catalunya in Spain in 2008-2009. His research interests are in the field of dynamics, control and optimization of biotechnological processes. He has been vice-chair and then chair of the technical committee on Biosystems and Bioprocesses of the International Federation of Automatic Control (IFAC) from 2001 to 2007. In 2008, he was awarded an honorary doctorate from Faculté Polytechnique de Mons in Belgium and in 2009 the D.G. Fisher Award from the Systems and Control Division of the Canadian Society for Chemical Engineering. In June 2010, he was inducted Fellow of the Canadian Academy of Engineering.
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