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Van Calster, B., Van Belle, V., Vergouwe, Y., Timmerman, D., Van Huffel, S., Steyerberg, E. (2012). Extending the c-statistic to nominal polytomous outcomes : The polytomous discrimination index. Statistics in Medicine, accepted.
Van Belle, V., Van Calster, B., Timmerman, D., Bourne, T., Bottomley, C., Valentin, L., Neven, P., Van Huffel, S., Suykens, J., Boyd, S. (2012). A mathematical model for interpretable clinical decision support with applications in gynecology. PLoS One, 7 (3), 1-10.
Bottomley, C., Van Belle, V., Pexsters, A., Papageorghiou, A., Mukri, F., Kirk, E., Van Huffel, S., Timmerman, D., Bourne, T. (2011). A model and scoring system to predict outcome of intrauterine pregnancies of uncertain viability. Ultrasound in Obstetrics & Gynecology, 37 (5), art.nr. 10.1002/uog.9007, 588-95.
Van Belle, V., Decock, J., Hendrickx, W., Brouckaert, O., Pintens, S., Moerman, P., Wildiers, H., Paridaens, R., Christiaens, M., Van Huffel, S., Neven, P. (2011). Short term prognostic index for breast cancer : NPI or Lpi. Pathology Research International, 1-7.
Van Belle, V., Pelckmans, K., Suykens, J., Van Huffel, S. (2011). Learning Transformation Models for Ranking and Survival Analysis. Journal of Machine Learning Research, 12, 819-862.
Van Belle, V., Pelckmans, K., Van Huffel, S., Suykens, J. (2011). Improved performance on high-dimensional survival data using survival SVM. Bioinformatics, 27 (1), 87-94.
Van Belle, V., Pelckmans, K., Van Huffel, S., Suykens, J. (2011). Support vector methods for survival analysis : a comparison between ranking and regression approaches. Artificial Intelligence in Medicine, 53 (2), 107-118.
Van Belle, V., Van Calster, B., Brouckaert, O., Vanden Bempt, I., Pintens, S., Harvey, V., Murray, P., Naume, B., Wiedswang, G., Paridaens, R., Moerman, P., Amant, F., Leunen, K., Smeets, A., Drijkoningen, M., Wildiers, H., Christiaens, R., Vergote, I., Van Huffel, S., Neven, P. (2010). Qualitative assessment of the progesterone receptor and HER2 improves the Nottingham Prognostic Index up to 5 years after breast cancer diagnosis. Journal of Clinical Oncology, 28 (27), 4129-4134.
Van Holsbeke, C., Van Belle, V., Leone, F., Guerriero, S., Paladini, D., Melis, G., Greggi, S., Fischerova, D., de Jonge, E., Neven, P., Bourne, T., Valentin, L., Van Huffel, S., Timmerman, D. (2010). Prospective external validation of the ovarian crescent sign as a single ultrasound parameter to distinguish between benign and malignant adnexal pathology. Ultrasound in Obstetrics & Gynecology, 36 (1), 81-87.
Van Belle, V., Pelckmans, K., Suykens, J., Van Huffel, S. (2010). Additive survival least squares support vector machines. Statistics in Medicine, 29 (2), 296-308.
Dieudonné, A., Van Belle, V., Neven, P. (2010). Association between CYP2D6 polymorphisms and breast cancer outcomes. Journal of the American Medical Association, 303 (6), 516-517.
Van Holsbeke, C., Zhang, J., Van Belle, V., Paladini, D., Guerriero, S., Czekierdowski, A., Muggah, H., Ombelet, W., Jurkovic, D., Testa, A., Valentin, L., Van Huffel, S., Bourne, T., Timmerman, D. (2010). Acoustic streaming cannot reliably discriminate between endometriomas and other types of adnexal lesions: a multicenter study of 633 adnexal masses. Ultrasound in Obstetrics & Gynecology, 35 (3), 349-353.
Bottomley, C., Van Belle, V., Mukri, F., Kirk, E., Van Huffel, S., Timmerman, D., Bourne, T. (2009). The optimal timing of an ultrasound scan to assess the location and viability of an early pregnancy. Human Reproduction, 24 (8), 1811-1817.
Pintens, S., Neven, P., Drijkoningen, M., Van Belle, V., Moerman, P., Christiaens, M., Smeets, A., Wildiers, H., Vanden Bempt, I. (2009). Triple negative breast cancer: a study from the point of view of basal CK5/6 and HER-1. Journal of Clinical Pathology, 62 (7), 624-628.
Brouckaert, O., Pintens, S., Van Belle, V., Van Huffel, S., Camerlynck, E., Amant, F., Smeets, A., Leunen, K., Van Limbergen, E., Berteloot, P., Hendrickx, W., Decock, J., Weltens, C., Van den Bogaert, W., Vanden Bempt, I., Paridaens, R., Drijkoningen, M., Wildiers, H., Vergote, I., Christiaens, M., Neven, P., Leunen, K. (2009). Short-term outcome of primary operated early breast cancer by hormone and HER-2 receptors. Breast Cancer Research and Treatment, 115 (2), 349-358.
Van Belle, V., Van Calster, B., Wildiers, H., Van Huffel, S., Neven, P. (2009). Lymph node ratio is a better prognostic predictor for disease free survival than the number of positive lymph nodes in Node-Positive Breast Cancer. Journal of Clinical Oncology, 27 (30), 150-151.
Testa, A., Timmerman, D., Van Belle, V., Fruscella, E., Van Holsbeke, C., Savelli, L., Ferrazzi, E., Leone, F., Marret, H., Tranquart, F., Exacoustos, C., Nazzaro, G., Bokor, D., Magri, F., Van Huffel, S., Ferrandina, G., Valentin, L. (2009). Intravenous contrast ultrasound examination using contrast-tuned imaging (CnTITM) and the contrast medium Sono Vue for discrimination between benign and malignant adnexal masses with solid components. Ultrasound in Obstetrics & Gynecology, 34, 699-710.
Neven, P., Van Calster, B., Vanden Bempt, I., Van Huffel, S., Van Belle, V., Hendrickx, W., Decock, J., Wildiers, H., Paridaens, R., Amant, F., Leunen, K., Berteloot, P., Timmerman, D., Van Limbergen, E., Weltens, C., Van den Bogaert, W., Smeets, A., Vergote, I., Christiaens, M., Drijkoningen, M. (2008). Age interacts with the expression of steroid and HER-2 receptors in operable invasive breast cancer. Breast Cancer Research and Treatment, 110 (1), 153-159.
Neven, P., Brouckaert, O., Van Belle, V., Vanden Bempt, I., Hendrickx, W., Cho, H., Deraedt, K., Van Calster, B., Van Huffel, S., Moerman, P., Amant, F., Leunen, K., Smeets, A., Wildiers, H., Paridaens, R., Vergote, I., Christiaens, M. (2008). In early-stage breast cancer, the estrogen receptor interacts with correlation between human epidermal growth factor receptor 2 status and age at diagnosis, tumor grade, and lymph node involvements. Journal of Clinical Oncology, 26 (10), 1768-1769.
Decock, J., Hendrickx, W., Vanleeuw, U., Van Belle, V., Van Huffel, S., Christiaens, M., Ye, S., Paridaens, R. (2008). Plasma MMP1 and MMP8 expression in breast cancer: protective role of MMP8 against lymph node metastasis. BMC Cancer, 8, 77-85.
Neven, P., Van Belle, V., Brouckaert, O., Pintens, S., Paridaens, R., Christiaens, M., Deraedt, K., Moerman, P. (2008). Are gene signatures better than traditional clinical factors?. The Lancet Oncology, 9 (3), 197-198.
Van Belle, V., Van Huffel, S., Suykens, J., Boyd, S. (2012). Interval coded scoring systems for survival analysis. Proc. of the European Symposium on Artificial Neural Networks. European Symposium on Artificial Neural Networks. Brugge, Belgium, Apr. 2012 (pp. 173-178).
Van Belle, V., Pelckmans, K., Suykens, J., Van Huffel, S. (2010). On the use of a clinical kernel in survival analysis. Prof. of the European symposium on Artificial Neural Networks (ESANN 2010). European symposium on Artificial Neural Networks (ESANN 2010). Brugge, Belgium, Apr. 2010 (pp. 451-456).
Van Belle, V., Pelckmans, K., Suykens, J., Van Huffel, S. (2009). Feature Selection in Survival Least Squares Support Vector Machines with Maximal Variation Constraints. In Cabestany, J. (Ed.), Sandoval, F. (Ed.), Prieto, A. (Ed.), Corchabo, J. (Ed.), Bio-Inspired Systems: Computational and Ambient Intelligence. Lecture notes in Computer Science: Vol. 5517. 10th International Work-Conference on Artificial Neural Networks, IWANN 2009, 2009 (pp. 65-72) Springer.
Van Belle, V., Pelckmans, K., Suykens, J., Van Huffel, S. (2009). MINLIP: Efficient Learning of Transformation Models. Lecture Notes in Computer Science: Vol. 5768. International Conference on Artificial Neural Networks (ICANN2009), 2009 (pp. 60-69) Springer.
Neven, P., Van Belle, V., Vanden Bempt, I., Deraedt, K., Moerman, P., Paridaens, R., Leunen, K., Smeets, A., Wildiers, H., Christiaens, M. (2008). The oestrogen receptor interacts with the correlation between HER-2 over-expression and age at diagnosis, tumour grade and lymph node involvement in operable breast cancer: a single centre experience. European Journal of Cancer Supplements: Vol. 6 (7). European Breast Cancer Conference. Berlin, Germany, 15-19 April, 2008 (pp. 85-86) Pergamon/Elsevier.
Van Calster, B., Van Belle, V., Condous, G., Bourne, T., Timmerman, D., Van Huffel, S. (2008). Multi-class AUC metrics and weighted alternatives. Proc. of the 21st International Joint Conference on Neural Networks (IJCNN2008). 21st International Joint Conference on Neural Networks (IJCNN2008). Hong Kong, China, Jun. 2008 (pp. 1391-1397).
Van Belle, V., Pelckmans, K., Suykens, J., Van Huffel, S. (2008). Survival SVM : a Practical scalable algorithm. Proc. of the 16th European Symposium on Artificial Neural Networks (ESANN 2008). 16th European Symposium on Artificial Neural Networks (ESANN 2008). Bruges, Belgium, Apr. 2008 (pp. 89-94).
Van Belle, V., Pelckmans, K., Suykens, J., Van Huffel, S. (2007). Support vector machines for survival analysis. Proc. of the Third International Conference on Computational Intelligence in Medicine and Healthcare (CIMED2007). Third International Conference on Computational Intelligence in Medicine and Healthcare (CIMED2007). Plymouth, England, Jul. 2007.
Van Belle, V., Poullet, J., Monleon, D., Celda, B., Martinez-Bisba, M., Van Huffel, S. (2006). Classification of brain tumors by means of high resolution magic angle spinning spectra. Proc. of the Belgian Day on Biomedical Engineering IEEE/EMBS Symposium. Belgian Day on Biomedical Engineering IEEE/EMBS Symposium. Brussels, Belgium, Dec. 2006 (pp. 199-202).
Dierickx, I., Van Belle, V., Vandorpe, T., Wildiers, H., Leunen, K., Peeters, S., Moermani, P., Deraedt, K., Christiaens, M., Neven, P. (2010). A prognostic model for breast cancer-related events in primary operated invasive lobular breast cancers from one centre. European Journal of Cancer Supplements: vol. 8 (3). European Breast Cancer Conference. Barcelona, Spain, 24-27 March 2010, 94-94.
Cho, H., Van Belle, V., Vandorpe, T., Wildiers, H., Janssen, H., Leunen, K., Amant, F., Vergote, I., Berteloot, P., Smeets, A., Van Limbergen, E., Weltens, C., Paridaens, R., Van Huffel, S., Christiaens, M., Neven, P. (2009). Prognostic Significance of Nodal and PgR Status on Early Relapse in Operable HER-2 Positive Breast Cancer from the Pre-Trastuzumab Era. Cancer Research: vol. 69 (24). San Antonio Breast Cancer Conference. San Antonio, USA, 9-13 December 2009, 837S-838S, Abstract No. 6046.
Van Belle, V., Van Calster, B., Van Huffel, S., Brouckaert, O., Vanden Bempt, I., Pintens, S., Paridaens, R., Christiaens, M., Neven, P. (2008). Improved NPI for breast cancer prognosis. European Journal of Cancer Supplements: vol. 6 (7), 190-190.
Van Belle, V., Van Huffel, S. (sup.), Suykens, J. (sup.) (2010). Non-Linear Survival Models and Their Applications Within Breast Cancer Prognosis (Niet-lineaire overlevingsmodellen en hun toepassingen in borstkankerprognose), 210 pp.
Two OPTEC professors have been awarded three "Gouden Krijtjes", the yearly teaching awards given by the organization of engineering students (vtk). Prof. Lombaert was awarded the prize for the best course in civil engineering, and Prof. Diehl the prizes for the best professor and the best course in mathematical engineering (where he teaches numerical optimization). They received these awards at the yearly "proffentap" where experienced students taught them how to draft beer professionally.
