Welcome
Our laboratory is of interested in understanding the role of ion channels in brain function and disease. Specifically, our research is aimed at understanding the relationship between structure, function and pharmacology of different classes of ion channels.
Ion channels are integral membrane proteins that act as molecular switches of electrochemical signaling in the central nervous system. To understand the mechanisms that underly functional and pharmacological properties of ion channels we use a combination of X-ray crystallography and electrophysiology. Combined, this approach opens new avenues for rational design of new drugs to treat disorders associated with dysfunctional ion channels.
The Laboratory of Structural Neurobiology is part of the Department of Cellular and Molecular Medicine within the Faculty of Medicine.
